研究業績


・2015年

Kai M, Ueno N, Kinoshita N. Phosphorylation-dependent ubiquitination of paraxial protocadherin (PAPC) controls gastrulation cell movements. PLoS ONE 10, e0115111, 2015

Nakajima Y Signaling regulating inner ear development: cell fate determination, patterning, morphogenesis, and defects. Cong Anomalies 55:17-25, 2015

Narematsu M, Kamimura T, Yamagishi T, Fukui M, Nakajima Y. Impaired development of left anterior heart field by ectopic retinoic acid causes transposition of the great arteries. J Am Heart Assoc 2015,4:e001889 doi: 10.1161/JAHA.115.001889 pp1-11

・2014年

Masuda T, Sakuma C, Nagaoka A, Yamagishi T, Ueda S, Nagase T, Yaginuma H. Follistatin-like 5 is expressed in restricted areas of the adult mouse brain: Implications for its function in the olfactory system. Masuda T, Sakuma C, Nagaoka A, Yamagishi T, Ueda S, Nagase T, Yaginuma H. Congenit Anom 2014 54, 63-66.

Morita W., Yano W., Nagaoka T., Abe M., Ohshima H., Nakatsukasa M.  Patterns of morphological variation in enamel–dentin junction and outer enamel surface of human molars. Journal of Anatomy 224:669-80, 2014

Takahashi M, Yamagishi T, Narematsu M, Kamimura T, Kai M, Nakajima Y. The epicardium is required for sarcomeric maturation and cardiomyocyte growth in the ventricular compact layer mediated by TGFβ and FGF before the onset of coronary circulation. Congenital Anomalies 54:162-171, 2014.

プロメテウス解剖学アトラス 頭部/神経解剖第2版、監訳:坂井建雄、河田光博。訳:天野 修、五十嵐由美子、上田秀一、金澤英作、河田光博、北村清一郎、坂井建雄、佐藤二美、仙波恵美子、中島裕司、埴原恒彦、八木沼洋行 2014年1月1日発行 医学書院(東京)

 

・2013年

Masuda T, Sakuma C, Ueno T, Yamada Y, Ohmomo H, Ueda S, Yamagishi T, Yaginuma H. Spatiotemporal patterns of the Huntingtin-interacting protein 1-related gene in the mouse head. Congenit Anom 2013 53, 141-148.

Masuda T, Taniguchi M, Sakuma C, Yamagishi T, Ueda S, Kawaguchi M, Yaginuma H. Development of the dorsal ramus of the spinal nerve in the mouse embryo: involvement of semaphorin 3A in dorsal muscle innervation. Congenit Anom 53, 122-126, 2013.

Nakajima Y. Imanaka-Yoshida K. New insights into the developmental mechanisms of coronary vessels and epicardium. Int Rev Cell Mol Biol 303, 263-317, 2013

長岡朋人、安部みき子、蔦谷匠、川久保善智、坂上和弘、森田航、米田譲、宅間仁美、八尋亮介、平田和明、稲原昭嘉 明石市雲晴寺近世墓地から出土した明石藩家老親族の人骨.人類誌 121、31‐48. 2013

 

・2012年

Sakabe S, Kokubo H, Nakajima Y, Saga Y. Ectopic retinoic acid signaling affects outflow tract cushion development through suppression of myocardial Tbx2-TGFβ2 pathway. Development 139, 385-395, 2012.

Takahashi M, Terasako Y, Yanagawa N, Kai M, Yamagishi T, Nakajima Y. Myocardial progenitors in the pharyngeal regions migrate to distinct conotruncal regions. Dev Dyn 241, 284-293, 2012

Nagaoka T, Abe M, Shimatani K. Estimation of mortality profiles from non-adult human skeletons in Edo-period Japan. Anthropological Science 120, 115-128, 2012

Yamagishi T, Ando K, Nakamura H, Nakajima Y. Expression of TGFβ2 gene during chick embryogenesis. Anat Rec 295, 257-267, 2012.

Tada M, Kai M. Planar cell polarity in coordinated and directed movements. Curr Top Dev Biol 101, 77-110, 2012

 

・2011年

Masuda T, Sakuma C, Yamagishi T, Ueno T, Yamada Y, Yaginuma H. Molecular cloning and expression pattern of the splicing variant of chick neuron navigator 2.  Saito Ho-on Kai Museum of Natural History Research Bulletin 75, 7-17, 2011.

Yanagawa N, Sakabe M, Sakata H, Yamagishi T, Nakajima Y. Nodal signal is required for morphogenetic movements of epiblast layer in the pre-streak chick blastoderm.  Dev Growth Differ 53, 366-377, 2011.

Ando K, Takahashi M, Yamagishi T, Miyagawa-Tomita S, Imanaka-Yoshida K, Yoshida T, Nakajima Y. Tenascin C may regulate the recruitment of smooth muscle cells during coronary artery development. Differentiation 81, 299-306, 2011.

Suzuki S., Abe  M., Motokawa M.,  Allometric Comparison of Skulls from Two Closeiy Related Weasels, Mustela itatsi and M. sibirica.Zoological Sience 28,676-688,2011

 

・2010年

Nakajima Y. Second lineage of heart forming region provides new understanding of conotruncal heart defects.  Congenital Anomalies 50, 8-14, 2010

Nakajima Y. Quick dissection of the segmental bronchi. Ant Sci Ed 3, 213-215, 2010.

Takahashi M, Abe M, Yamagishi T, Nakatani K, Okade T, Ogawa T, Konishi H, Kiryu-Seo S, Kiyama H, Nakajima Y. Local ventilation system successfully reduced formaldehyde exposure during gross anatomy dissection classes. Anat Sci Int, 85, 251-252, 2010.

 

・2009年

Yanagawa N, Nakajima Y. A simple dissection method for the conduction system of the human heart. Anat Sci Ed 2, 78-80, 2009.

Nakajima Y, Sakabe M, Matsui H, Sakata H, Yanagawa N, Yamagishi T. Heart Development before beating. Anat Sci Int 84, 67-76, 2009

プロメテウス解剖学アトラス 頭部/頚部、監訳:坂井建雄、河田光博。訳:五十嵐由美子、上田秀一、金澤英作、河田光博、北村清一郎、佐藤二美、仙波恵美子、中島裕司、柳沼洋行 2009年2月1日発行 医学書院(東京)

 

・2008年

Kitano A, Yamanaka O, Ikeda K, Ishida-Nishikawa I, Okada Y, Shirai K, Saika S. Tetrandrine suppresses activation of human subconjunctival fibroblasts in vitro. Curr Eye Res 33;559-565: 2008.

Matsui H, Sakabe M, Sakata H, Yanagawa N, Ikeda K, Yamagishi T, Nakajima Y. Induction of initial heart α-actin, smooth muscle α-actin, in chick pregastrula epiblast: The role of hypoblast and fibroblast growth factor-8. Develop Growth Differ 50, 143-157, 2008.

Miyazaki K, Okada Y, Yamanaka O, Kitano A, Ikeda K, Kon S, Uede T, Rittling SR, Denhardt DT, Kao WW, Saika S. Corneal wound healing in an osteopomtin-deficient mouse. Invest Ophthalmol Vis Sci 49;1367-1375: 2008.

Otogawa K, Ogawa T, Shiga R, Nakatani K, Ikeda K, Nakajima Y, Kawada N. Attenuation of acute and liver injury in rats by iron-deficient diet. Am J Physiol Regul Integr Comp Physiol 294, R311-R320, 2008.

Saika S, Yamanaka O, Flanders KC, Okada Y, Miyamoto T, Sumioka T, Shirai K, Kitano A, Miyazaki K, Tanaka S, Ikeda K. Epithelial-mesenchymal transition as a theraeutic target for prevention of ocular tissue fibrosis. Endocr Metab Immune Disord Drug Targets 8;69-76: 2008.

Sakabe M, Sakata H, Matsui H, Ikeda K, Yamagishi T, Nakajima Y. ROCK1 expression is regulated by TGFbeta3 and ALK2 during valvuloseptal endocardial cushion formation. Anat Rec (Hoboken) 291;845-857: 2008.

Sumioka T, Ikeda K, Okada Y, Yamanaka O, Kitano A, Saika S. Inhibitory effect of blocking TGF-beta/Smad signal on injury-induced fibrosis of corneal endothelium. Mol Vis 14;2272-2281: 2008.

 

・2007年

El-Karef A, Kaito M, Tanaka H, Ikeda K, Nishioka T, Fujita N, Inada H, Adachi Y, Kawada N, Nakajima Y, Imanaka-Yoshida K, Yoshida T. Expression of large tenascin-C splice variants by hepatic stellate cells/myofibroblasts in chronic hepatitis C. J Hepatol 46; 664-673: 2007.

Fujita S, Saika S, Kao WW, Fujita K, Miyamoto T, Ikeda K, Nakajima Y, Ohnishi Y. Endogenous TNFalpha suppression of neovascularization in corneal stroma in mice. Invest Ophthalmol Vis Sci 48; 3051-3055: 2007.

Kitano A, Saika S, Yamanaka O,Ikeda K , Okada Y, Shirai K, Reinach PS. Emodin suppression of ocular surface inflammatory reaction. Invest Ophthalmol Vis Sci 48; 5013-5022: 2007.

Kinoshita K, Iimuro Y, Otogawa K, Saika S, Inagaki Y, Nakajima Y, Kawada N, Fujimoto J, Friedman SL, Ikeda K. Adenovirus-mediated expression of BMP-7 suppresses the development of liver fibrosis in rats. Gut 56; 706-14: 2007.

Nagaoka T., Abe M.Human skeletal remains from the Osaka castle in Japan:metrics and weapon injuries.Anthropological science 115; 163-168: 2007.

Okada Y, Ikeda K, Yamanaka O, Miyamoto T, Kitano A, Kao WW, Saika S. TNFalpha suppression of corneal epithelium migration. Mol Vis 13; 1428-1435: 2007.

Otogawa K, Kinoshita K, Fujii H, Sakabe M, Shiga R, Nakatani K, Ikeda K, Nakajima Y, Ikura Y, Ueda M, Arakawa T, Hato F, Kawada N. Erythrophagocytosis by liver macrophages (Kupffer cells) promotes oxidative stress, inflammation, and fibrosis in a rabbit model of steatohepatitis: implications for the pathogenesis of human nonalcoholic steatohepatitis. J Am Pathol 170; 967-980: 2007.

Sakata H, Sakabe M, Matsui H, Kawada N, Nakatani K, Ikeda K, Yamagishi T, Nakajima Y. Rho kinase inhibitor Y27632 affects initial heart myofibrillogenesis in cultured chick blastoderm. Dev Dyn 2007;236:461-472.

Saika S, Yamanaka O, Nishikawa-Ishida I, Kitano A, Flanders KC, Okada Y, Ohnishi Y, Nakajima Y, Ikeda K. Effect of Smad7 gene overexpression on transforming growth factor beta-induced retinal pigment fibrosis in a proliferative vitreoretinopathy mouse model. Arch Ophthalmol 125; 647-654: 2007.

Saika S, Yamanaka O, Okada Y, Miyamoto T, Kitano A, Flanders KC, Ohnishi Y, Nakajima Y, Kao WW, Ikeda K. Effect of overexpression of PPARgamma on the healing process of corneal alkali burn in mice. Am J Physiol Cell Physiol 293; C75-86: 2007.

Yamanaka O, Saika S, Ohnishi Y, Kim-Mitsuyama S, Kamaraju AK, Ikeda K. Inhibition of p38MAP kinase suppresses fibrogenic reaction in conjunctiva in mice. Mol Vis 13; 1730-1739: 2007.

 

・2006年

El-Karef A, Kaito M, Tanaka H, Ikeda K, Nishioka T, Fujita N, Adachi Y, Kawada N, Nakajima Y, Inada H, Imanaka-Yoshida K, Yoshida T. Expression of Large Tenascin-C Splice Variants by Hepatic Stellate Cells/Myofibroblasts in Chronic Hepatitis C. J Hepatol 2006 In press

Kitano A, Saika S, Yamanaka O, Reinach PS, Ikeda K, Okada Y, Shirai K, Ohnishi Y. Genipin suppresses fibrogenic behaviors of a-TN4 lens cell line.
J Cataract Refract Surg 32(10):1727-1735;2006.

Kitano A, Saika S, Yamanaka O, Ikeda K, Reinach PS, Nakajima Y, Okada Y, Shirai K, Ohnishi Y. Genipin-suppresses subconjunctival fibroblast migration, proliferation and myofibroblast transdifferentiation Ophthalmic. Res 38(6):355-360;2006.

Kinoshita K, Iimuro Y, Fujimoto J, Inagaki Y, Namikawa K, Kiyama H, Nakajima Y, Otogawa K, Kawada N, Friedman SL, Ikeda K. Targeted and Regulable Expression of Transgenes in Hepatic Stellate Cells and Myofibroblasts in Culture and in vivo Using an Adenoviral Cre-LoxP System to Antagonize Hepatic Fibrosis. Gut 2006 In press

Kinoshita K, Iimuro Y, Otogawa K, Saika S, Inagaki Y, Nakajima Y, Kawada N, Fujimoto J, Friedman SL, Ikeda K. Adenovirus-mediated expression of BMP-7 suppresses the development of liver fibrosis in rats. Gut 2006 In press

Ishizaka S, Ouji Y, Yoshikawa M, Nakatani K. Derivation and characterization of hepatocytes from embryonic stem cells in vitro. In: Turksen K (ed), Methods in Molecular Biology, vol. 330: Embryonic Stem Cell Protocols, second edition, volume 2, Human Press Inc. Totowa, NJ 387-399;2006.

Izumi N, Mizuguchi S, Inagaki Y, Saika S, Kawada N, Nakajima Y, Inoue K, Suehiro S, Friedman SL, Ikeda K. BMP-7 opposes TGF-beta1-mediated collagen induction in mouse pulmonary myofibroblasts through Id2. Am J Physiol Lung Cell Mol Physiol 290:L120-6;2006.

Matsui H, Sakabe M, Sakata H, Nakatani K, Ikeda K, Fukui M, Ando K, Yamagishi T, Nakajima Y. Heart myofibrillogenesis occurs in isolated chick posterior blastoderm:ハa culture model. Acta Histochem Cytochem 39:139-144, 2006.

Nakatani K, Tanaka H, Ikeda K, Sakabe M, Kadoya H, Seki S, Kaneda K, Nakajima Y. Expression of NCAM in the activated portal fibroblasts during regeneration of the rat liver after partial hepatectomy. Arch Histol Cytol 69 : 61-72; 2006.

Saika S, Ikeda K, Yamanaka O, Flanders KC, Ohnishi Y, Nakajima Y, Muragaki Y, Ooshima A.  Adenoviral gene transfer of BMP-7, Id2, or Id3 suppresses injury-induced epithelial-to-mesenchymal transition of lens epithelium in mice. Am J Physiol Cell Physiol 290: C282-9; 2006.

Saika S, Ikeda K , Yamanaka O, Flanders KC, Okada Y, Miyamoto T, Kitano A, Ooshima A, Nakajima Y , Ohnishi Y, Kao WW. Loss of TNFa potentiates TGFb-mediated pathogenic tissue response during wound healing. Am J Pathol 168(6):1848-1860, 2006.

Saika S, Yamanaka O, Nishikawa-Ishida I, Kitano A, Flanders KC, Okada Y, Ohnishi Y, Nakajima Y, Ikeda K. Smad7 gene overexpression suppresses TGFb-induced retinal pigment fibrosis in a PVR mouse model.Arch Ophthalmol-Chic 2006 In press

Sakabe M, Ikeda K, Nakatani K, Kawada N, Imanaka-Yoshida K, Yoshida T, Yamagishi T, Nakajima Y. Rho kinases regulate endothelial invasion and migration during valvuloseptal endothelial cushion tissue formation. Dev Dyn 235(1):94-104;2006.

Sugawara K, Turuta D, Kobayashi H, Ikeda K, Hopkinson SB, Jones JC, Ishii M. Spatial and temporal control of laminin-332 (5) and -511 (10) expression during induction of anagen hair growth. J Histochem Cytochem 2006 In press

Wang YQ, Luk JM, Chu AC, Ikeda K, Man K, Kaneda K, Fan ST. TNP-470 blockage of VEGF synthesis is dependent on MAPK/COX-2 signaling pathway in PDGF-BB-activated hepatic stellate cells. Biochem Biophys Res Commun 3;341: 239-44;2006.

Yamanaka O, Saika S, Ikeda K, Miyazaki K, Ohnishi Y, Ooshima A.
Interleukin-7 modulates extracellular matrix production and tgf-Beta signaling in cultured human subconjunctival fibroblasts. Curr Eye Res 31(6):491-499;2006.

Yamanaka O, Ikeda K, Saika S, Miyazaki K, Ooshima A, Ohnishi Y. Gene transfer of Smad7 modulates injury-induced conjunctival wound healing in mice. Mol Vis 12: 841-851;2006.

 

・2005年

Fujii H, Seki S, Kobayashi S, Kitada T, Kawakita N, Adachi K, Tsutsui H,
Nakanishi K, Fujiwara H, Ikarashi Y, Taniguchi M, Mitchell K, Ikemoto M,
Nakajima Y, Arakawa T, Kaneda K. A murine model of NKT cell-mediated liverinjury induced by alpha-galactosylceramide/d-galactosamine. Virchows Arch. Jun;446(6):663-73, 2005.

Inagaki Y, Kushida M, Higashi K, Itoh J, Kawada N, Namikawa K, Kiyama H, Bou-Gharios G, Higashiyama R, Watanabe T, Okazaki I, Ikeda K. Cell type-specific intervention of TGF-beta/Smad signaling suppresses collagen gene expression and hepatic fibrosis in mice. Gastroenterology 129(1): 259-268, 2005.


Matsui H, Ikeda K, Nakatani K, Sakabe M, Yamagishi T, Nakanishi T, Nakajima Y. Induction of initial cardiomyocyte a-actin - smooth muscle a-actin - in cultured avian pregastrula epiblast: a role for nodal and BMP antagonist. Dev Dyn 233 (4): 1419-1429, 2005.

Matsui H, Kawada N. Effect of S-adenosyl-l-methionine on the activation, proliferation and contraction of hepatic stellate cells. Europ J Pharmacol 509(1): 31-36, 2005.

Nakatani K, Ikeda K, Nakajima Y, Seki S. Expression of molecules with a potential for modulating interaction with extracellular matrices on hepatic stellate cells: neural cell adhesion molecules and osteonectin. In: Liver Cirrhosis One, Nova Science Publishers Inc, NY in press

Saika S, Ikeda K, Yamanaka O, Flanders KC, Nakajima Y, Miyamoto T, Ohnishi Y, Kao WW, Muragaki Y, Ooshima A. Therapeutic effects of adenoviral gene transfer of bone morphogenic protein-7 on a corneal alkali injury model in mice. Lab Invest. 85(4): 474-486, 2005

Saika S, Ikeda K, Yamanaka O, Miyamoto T, Ohnishi Y, Sato M, Muragaki Y, Ooshima A, Nakajima Y, Kao WWY, Flamders KC, Roberts AB. Expression of Smad7 in mouse eyes accelerates healing of corneal tissue after exposure to alkali. Am. J. Pathol. 166(5): 1405-1418, 2005

Saika S, Miyamoto T, Yamanaka O, Kato T, Ohnishi Y, Flamders KC, Ikeda K, Nakajima Y, Kao WWY, Sato M, Muragaki Y, Ooshima A. Therapeutic effect of topical administration of SN50, an inhibitor of nuclear factor-kB, in treatment of corneal alkali burns in mice. Am. J. Pathol. 166(5): 1393-1403,2005

Saika S, Yamanaka O, Ikeda K, Mitsuyama SK, Flanders KC, Yoo J, Roberts AB, Nishikawa-Ishida I, Ohnishi Y, Muragaki Y, Ooshima A. Inhibition of p38MAP kinase suppresses fibrotic reaction of retinal pigment epithelial cells. Lab Invest. 2005 in press

Sakabe M, Matsui H, Sakata H, Ando K, Yamagishi T, Nakajima Y. understanding heart development and congenital heart defects through developmental biology: A segmental approach. Cong Anom, 45(4):107-18, 2005

安部みき子 脊椎動物の顎骨の進化―肉食をする哺乳類の顎―, Clinical Calcium 15(7):1258-1261, 2005

仲谷和記、池田一雄、坂部正英、河田則文、中島裕司. 肝発生過程における肝芽組織での接着分子発現に関する研究. 肝サイトスケレトン研究会誌(岡上武 編):第15巻, 33-36, 2005

 

・2004年
Ando K, Nakajima Y, Yamagishi T, Yamamoto Y, Nakamura H. Development of proximal coronary arteries in quail embryonic heart: multiple capillaries penetrating the aortic sinus fuse to form main coronary trunk. Circ Res 94 (Feb): 346 - 352, 2004

Matsui H, Ikeda K, Nakajima Y, Horikawa S, Imanishi Y, Kawada N. Sulfur-containing amino acids attenuate the development of liver fibrosis in rats through down-regulation of stellate cell activation. Journal of Hepatology 40(6): 917-925, 2004

Nakatani K, Okuyama H, Shimahara Y, Saeki S, Kim DH, Nakajima Y, Seki S, Kawada N, Yoshizato K.
Cytoglobin/STAP, its unique localization in splanchnic fibroblast-like cells and function in organ fibrogenesis. Lab Invest 84 (1): 91-101, 2004.

Nakatani K, Kaneda K, Seki S, Nakajima Y. Pit cells as liver-associated natural killer cells: morphology and function. Med Electron Microsc 37 (1): 29-36, 2004

Saika S, Ikeda K, Yamanaka O, Sato M, Muragaki Y, Ohnishi Y, Ooshima A, Nakajima Y, Namikawa K, Kiyama H, Flanders KC, Roberts AB. Transient adenoviral gene transfer of Smad7 prevents injury-induced epithelial-mesenchymal transition of lens epithelium in mice. Lab Invest. 84(10): 1259-1270, 2004

Wang YQ, Luk JM, Ikeda K, Man K, Chu AC, Kaneda K, Fan ST. Regulatory role of vHL/HIF-1alpha in hypoxia-induced VEGF production in hepatic stellate cells. Biochem Biophys Res Commun 317(2): 358-62 , 2004

Yamagishi T, Nakajima Y, Nishimatsu S, Nohno T, Ando K, Nakamura H. Expression of tbx20 RNA during chick heart development. Dev Dyn 230, 576-580, 2004.

Yamamoto S, Okuda T, Yamasaki K, Tanaka H, Kubo S, Takemura S, Ikeda K, Minamiyama Y, Hirohashi K, Suehiro S. FK778 and FK506 combination therapy to control acute rejection after rat liver allotransplantation. Transplantation. 78(11): 1618-1625, 2004

安部みき子 脊椎動物の顎骨の進化―Over view―, Clinical Calcium 14(11) :1771-1773, 2004

仲谷和記、河田則文、吉里勝利. 生体の科学 初耳事典:Cygb/STAP. 生体の科学:55 (3), 273, 2004


・2003年
Fujii H, Seki S, Nakatani K, Ikeda K, Ikemoto M, Nakajima Y, Arakawa T, Kaneda K. Localization of lymphocyte apoptosis in murine lymphoid tissue after stimulation of natural killer T cell with alpfa-galactosylceramide. Arch. Histol. Cytol. 66(5): 397-406, 2003

Ikeda K, Friedman SL. Liver fibrosis and DDR2 signaling. Connective Tissue 35(3):165-168, 2003

Inagaki Y, Nemoto T, Kushida M, Sheng Y, Higashi K, Ikeda K, Kawada N, Shirasaki F, Takehara K, Sugiyama K, Fujii M, Yamauchi H, Nakao A, De Crombrugghe B, Watanabe T, Okazaki I. Interferon alfa down-regulates collagen gene transcription and suppresses experimental hepatic fibrosis in mice. Hepatology 38(4): 890-899, 2003

Kobayashi S, Seki S, Kawada N, Morikawa H, Nakatani K, Uyama N, Ikeda K, Nakajima Y, Arakawa T, Kaneda K. Apoptosis of T cells in the hepatic fibrotic tissue of the rat: a possible inducing role of hepatic myofibroblast-like cells. Cell Tissue Res. 311(3): 353-64, 2003

Maeda N, Kawada N, Seki S, Arakawa T, Ikeda K, Iwao H, Okuyama H, Hirabayashi J, Kasai K, Yoshizato K. Stimulation of proliferation of rat hepatic stellate cells by galectin-1 and galectin-3 through different intracellular signaling pathways. J Biol Chem. 278(21): 18938-44, 2003

Nakano M, Arai E, Nakajima Y, Nakamura H, Miyazono K, Hirose T. Immunohistochemical study of chondrolipoma: Possible importance of transforming growth factor (TGF)-betas, latent TGF-beta binding protein-1 (LTBP-1), and bone morphogenic protein (BMP) for chondrogenesis in lipoma. The Journal of Dermatology: Vol.30 (3) 189-195, 2003

Sato EF, Higashino M, Ikeda K, Wake R, Matsuo M, Utsumi K, Inoue M. Oxidative stress-induced cell death of human oral neutrophils. Am J Physiol Cell Physiol. 284(4): C1048-53, 2003

Seki S, Kitada T, Sakaguchi H, Nakatani K, Wakasa K. Pathological significance of oxidative cellular damage in human alcoholic liver disease. Histopathology 42 (4): 365-71, 2003

Sogawa M. Matsumoto T. Yamagami H. Yamada T. Ozeki Y. Yano I. Nakajima Y. Arakawa T. Kaneda K. A murine model of granulomatous colitis with mesenteric lymphadenitis induced by mycobacterial cord factor. Virchows Archiv. 442(2): 151-8, 2003.

Uyama N, Shimahara Y, Okuyama H, Kawada N, Kamo S, Ikeda K, Yamaoka Y. Carbenoxolone inhibits DNA synthesis and collagen gene expression in rat hepatic stellate cells in culture. J Hepatol 39(5): 749-55, 2003

圓藤陽子、安部みき子、中島裕司、木山博資、宮崎竹二、竹内靖人、小松晃雄、圓藤吟史。

光触媒蛍光灯による室内環境中ホルムアルデヒド濃度の低減化。生活衛生47: 261-268, 2003

小宮孟、小林理恵、安部みき子。千葉県武士遺跡出土イノシシの齢構成にもとづく屠殺基節と家畜イノシシの検討。人類誌111(2): 131-142, 2003

 

・2002年
Asahina K , Kawada N, Kristensen DB, Nakatani K, Seki S, Shiokawa M, Tateno C, Obara M, Yoshizato K. Characterization of Human stellate cell activation-associated protein (STAP) and its expression in human liver. Biochim Biophys Acta - Gene Structure and Expression 1577 (3): 471-475, 2002

Hara M, Ono K, Hwang MW, Iwasaki A, Okada M, Nakatani K, Sasayama S, Matsumori A. Evidence for a role of mast cells in the evolution to congestive heart failure. J Exp Med 195 (3): 375-381, 2002

Hiruma T, Nakajima Y, Nakamura H. Development of pharyngeal arch arteries in early mouse embryo. J Anat 201: 15-29, 2002

Ikeda K, Wang LH, Torres R, Zhao H, Olaso E, Eng FJ, Labrador P, Klein R, Lovett D, Yancopoulos GD, Friedman SL, Lin HC. Discoidin domain receptor 2 interacts with Src and Shc following its activation by type I collagen. J Biol Chem. May 24; 277(21): 19206-12 , 2002.

Ishizaka S, Shiroi A, Kanda S, Yoshikawa M, Tsujinoue H, Kuriyama S, Hasuma T, Nakatani K, Takahashi K. Development of hepatocytes from embryonic stem cells after transfection with the HNF-3b gene. FASEB J 16 (11): 1444-1446, 2002

Nakajima Y, Yamagishi T, Ando K, Nakamura H. Significance of bone morphogenetic protein-4 function in the initial myofibrillogenesis of chick cardiogenesis. Dev Biol 245: 291-303, 2002

Nakatani K, Seki S, Kawada N, Kitada T, Yamada T, Sakaguchi H, Kadoya H, Ikeda K, Kaneda K. Expression of SPARC by activated hepatic stellate cells and its correlation with the stages of fibrogenesis in human chronic hepatitis. Virchows Arch 441(5): 466-74, 2002

Saxena NK, Ikeda K, Rockey DC, Friedman SL, Anania FA. Leptin in hepatic fibrosis: evidence for increased collagen production in stellate cells and lean littermates of ob/ob mice. Hepatology 35(4): 762-71, 2002

Seki S, Kitada T, Kawada N, Kadoya H, Sakaguchi H, Nakatani K, Satake K. Fatty change in human hepatocellular carcinoma cell lines derived from patients with antibodies to hepatitis C virus. Hepatogastroenterology 49(44): 340-344, 2002

Seki S, Kitada T, Yamada T, Sakaguchi H, Nakatani K, Onoda N, Satake K. Immunohistochemical detection of 8-hydroxydeoxyguanosine, a marker of oxidative DNA damage, in human chronic. Histopathology 40(6): 531-535, 2002

Seki S, Kitada T, Yamada T, Sakaguchi H, Nakatani K, Wakasa K. In situ detection of lipid peroxidation and oxidative DNA damage in non-alcoholic fatty liver diseases. J Hepatol 37(1): 56-62, 2002

Olaso E, Labrador P, Wang LH, Ikeda K, Eng FJ, Klein R, Lovett DH, Lin HC, Friedman SL. DDR2 receptor regulates fibroblast proliferation and migration through extracellular matrix in association with transcriptional activation of MMP-2. J Biol Chem. Feb 277(5): 3606-13. 2002

 

・2001年
Kadoya H, Ikeda K, Nakatani K, Seki S, Kaneda K. Cellular prion protein expression in non-ciliated epithelial cells (Clara cells) of proliferating bronchioles during bleomycin-induced pulmonary fibrosis in hamster. Osaka City Med J. Jun 47(1): 23-32. 2001

Kobayashi S, Morikawa H, Nakatani K, Seki S, Kaneda K. Apoptosis of infiltrating leukocytes in concanavalin A-induced hepatic inflammation in rats. In: Wisse E, Knook DL, de Zanger R, Arthur MJP (ed), Cells of the hepatic sinusoid, vol. 8, Kupffer Cell Foundation, Leiden, the Netherlands, pp 59-61, 2001

Kawada N, Kristensen DB, Asahina K, Nakatani K, Minamiyama Y, Seki S, Yoshizato K. Characterization of a stellate cell activation-associated protein (STAP) with peroxidase activity found in rat hepatic stellate cells. J Biol Chem 276 (27): 25318-25323, 2001

Nakatani K, Seki S, Kawada K, Fujii H, Kobayashi S, Kadoya H, Ikeda K, Kaneda K. Expression of osteonectin in human hepatic stellate cells during chronic liver inflammation. In: Wisse E, Knook DL, de Zanger R, Arthur MJP (ed), Cells of the hepatic sinusoid, vol. 8, Kupffer Cell Foundation, Leiden, the Netherlands, pp 231-232, 2001

Nakajima Y, Yoshimura K, Nomura M, Nakamura H. Expression of HNK1 epitope by the cardiomyocytes of the early embryonic chick: In situ and in vitro study. Anat Rec 263: 326-333, 2001.

Nishimura H, Okazaki T, Tanaka Y, Nakatani K, Hara M, Matsumori A, Sasayama S, Mizoguchi A, Hiai H, Minato N, Honjo T. Autoimmune Dilated Cardiomyopathy in PD-1 Receptor-Deficient Mice. Science 291 (5502): 319-322, 2001

Olaso E, Ikeda K, Eng FJ, Xu L, Wang LH, Lin HC, Friedman SL. The DDR2 receptor promotes MMP-2-mediated proliferation and invasion by hepatic stellate cells. J Clin Invest. Nov; 108(9): 1369-78. 2001

Okuno M, Akita K, Moriwaki H, Kawada N, Ikeda K, Kaneda K, Suzuki Y, Kojima S. Prevention of rat hepatic fibrosis by the protease inhibitor, camostat mesilate, via reduced generation of active TGF-beta. Gastroenterology. Jun;120(7):1784-800. 2001
 
Yamagishi T, Nakajima Y, Nishimatsu S, Nohno T, Ando K, Nakamura H. Expression of bone morphogenetic protein-5 gene during chick heart development: possible roles in valvuloseptal endocardial cushion formation. Ant Rec 264: 313-316, 2001

安部みき子・岩田栄之 ニホンオオカミとモンゴルオオカミの頭骨について フォレスト・コールVol.8: 22-26, 2001