最近の業績
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リストマーク 2003
  Ryoji Maekura, Hiroaki Kohno, Atsusi Hirotani, Yosinari Okuda, Masami Itou, Masami Itou, and Ikuya Yano.  A Prospective Clinical Evaluation of the Serologic Tuberculous Glycolipid (TBGL) Test for the Diagnosis of Smear-Negative Pulmonary Tuberculosis Used in Combination with Nucleic Acid Amplification Test. J. Clinical Microbiology 2003; March in press.

Hirotani A, Maekura R, Okuda Y, Yoshimura K, Moriguchi K, Kitada S,
Hiraga T, Ito M, Ogura T, Ogihara T. Exercise-induced electrocardiographic changes in patients with chronic respiratory diseases: differential diagnosis by 99mTc-tetrofosmin SPECT. J Nucl Med 2003; 44: in press.

K. Miki, R. Maekura, T. Hiraga, Y. Okuda, T. Okamoto, A. Hirotani, and T. Ogura. Impairments and Prognostic Factors for Survival in Patients with Idiopathic Pulmonary Fibrosis. Respiratory Medicine in press.

Hirotani A, Maekura R, Okuda Y, Yoshimura K, Moriguchi K, Kitada S,
Hiraga T, 在宅酸素療法症例における介護保険制度の問題点と対策。日本呼吸器学会雑誌,2003; 印刷中。

Hiraga T, Hirotani A, Maekura R, Okuda Y, Yoshimura K, Moriguchi K, Kitada S,
Prognostic predictors for survival in patients with COPD using cardiopulmonary exercise testing. Clin Physiol Funct Imaging (2003), 300-307.

リストマーク 2002
  H. Hirano, T. Ichimura, M. Hanibuchi, M. Nakagawa, R. Maekura, M. Ito, T. Maeda, Y. Yoshii, H. Kuwabara, H. Mori. Anaplastic large-cell lymphoma (Ki-1 lymphoma): ultrastructural and immunohistochemical studies. Med Electron Microsc; 35, 153-159, 2002.

Seigo Kitada, Ryoji Maekura, Naomi Toyosima, Nagatosi Fujiwara, Ikuya Yano, Takesi Ogura, Masami Itou and Kazuo Kobayashi. Serodiagnosis of Pulmonary Disease due to Mycobacterium avium Complex with an Enzyme Immunoassay that Uses a Mixture of Glycopeptidelipid Antigens. Clinical Infectious Disease 2002; 35: 1328-35.

リストマーク 2001
  R. Maekura, Y. Okuda, M. Nakagawa, T. Hiraga, S. Yokota, M. Itou, I. Yano, H. Kohno, M. Wada, C. Abe, T. Toyoda, T. Kishimoto, and T. Ogura. Clinical Evaluation of Anti-Tuberculous Glycolipid Immunoglobulin G Antibody Assay for Rapid Serodiagnosis of Pulmonary Tuberculosis. J. Clinical Microbiology; 39 (10), 3603-3608, 2001

Maekura, R., Okuda, Y.,  Nakagawa, M. Hiraga, T., Yokota, S., Ito, M., IYano, I.,  Kohno, H., Wada M.,  Abe C.,  Toyoda, T.,  Kishimoto, T., and  Ogura. T. Clinical Evaluation of Anti-tuberculous Glycolipid Immunoglobulin-G Antibody Assay for Rapid Serodiagnosis of Pulmonary Tuberculosis J. Clin. Microbiol. 2001. 39: 3603-3608

Yamagami H., T. Matsumoto, N. Fujiwara, T. Arakawa, K. Kaneda, I. Yano, and K. Kobayashi. . Trehalose 6,6'-dimycolate (Cord factor) of Mycobacterium tuberculosis induces foreign-body- and hypersensitivity-type granulomas in mice. Infect. Immun. 2001. 69: 810-815.

Ueda S., N. Fujiwara, T. Naka, I. Sakaguchi, Y. Ozeki, I. Yano, T. Kasama, and K. Kobayashi.  Structure-activity relationship of mycoloyl glycolipids derived from Rhodococcus sp. 4306. Microb. Pathog. 2001. 30: 91-99.

Maeda, S., M. Matsuoka, N. Nakata, M. Kai, Y. Maeda, K. Hashimoto, H. Kimura, K. Kobayashi, and Y. Kashiwabara. 2001. Multidrug resistant Mycobacterium leprae from patients with leprosy. Antimicrob. Agents Chemother. 2001. 45: 3635-3639.

リストマーク 2000
Ohno, M., Yamaguchi, I., Yamamoto, I., Fukuda, T., Yokota, S., Maekura, R., Ito, M., Yamamoto, Y., Ogura, T., Maeda, K., Komuta, K., Igarashi, T., Azuma, J. Slow N-acetyltransferase 2 genotype affects the incidence of isoniazid and rifampicin-induced hepatotoxicity. Int J Tuberc Lung Dis. 2000. 4: 256-261.

 Nishiuchi, Y.,  Baba, T., and  Yano, I. Mycolic acids from Rhodococcus, Gordonia, and Dietzia. J. Microbiol. Meth. 2000.; 40: 1-9.

Hamasaki, N., K. Isowa, K. Kamada, Y. Terano, T. Matsumoto, T. Arakawa, K. Kobayashi, and I. Yano. . In vivo administration of mycobacterial cord factor (trehalose 6,6'-dimycolate) can induce lung and liver granulomas and thymic atrophy in rabbits. Infect. Immun. 2000. 68: 3704-3709.

Saita, N., N. Fujiwara, I. Yano, K. Soejima, and K. Kobayashi. Trehalose 6,6'-dimycolate/cord factor of Mycobacterium tuberculosis induces corneal angiogenesis in rats. Infect. Immun. 2000. 68: 5991-5997.

Matsuoka, M., S. Maeda, M. Kai, N. Nakata, G.-t. Chae, T. P. Gillis, K. Kobayashi, S. Izumi, and Y. Kashiwabara. Mycobacterium leprae typing by genomic diversity and global distribution of genotypes. Int. J. Lepr. Other Mycobact. Dis. 2000. 68: 121-128.

リストマーク 1997〜1999
Nishiuchi Y., Baba T., Hotta H. and  Yano I.. Mycolic acid analysis in Nocardia species. The mycolic acid compositions of Nocardia asteroides, N. farcinica, and N. nova. J. Microbiol. Meth. 1999. 37: 111-122.

Kawamura, M., Sueshige, N., Imayoshi, K., Yano, I., Maekura, R., Kohno, H. Enzyme immunoassay to detect antituberculous glycolipid antigen (anti-TBGL antigen) antibodies in serum for diagnosis of tuberculosis.
J Clin Lab Anal. 1997. 11: 140-145

Kai, M., M. Matsuoka, N. Nakata, S. Maeda, M. Gidoh, Y. Maeda, K. Hashimoto, K. Kobayashi, and Y. Kashiwabara.  Diaminodiphenylsulfone resistance of Mycobacterium leprae due to mutations in the dihydropteroate synthase gene. FEMS Microbiol. Lett. 1999. 177: 231-235.

Pan, J., N. Fujiwara, S. Oka, R. Maekura, T. Ogura, and I. Yano. Anti-cord factor (trehalose 6,6'-dimycolate) IgG antibody in tuberculosis patients recognizes mycolic acid subclasses. Microbiol. Immunol. 1999. 43: 863-869.

Wang, L., S. Izumi, H. He, N. Fujiwara, N. Saita, I. Yano, K. Kobayashi, and N. Tatsumi. Serodiagnosis of Hansen's disease/leprosy by enzyme-linked immunosorbent assay using cord factor (trehalose 6,6'-dimycolate) as an antigen. Jpn. J. Lepr. 1999. 68: 165-174.

Enomoto, K., S. Oka, N. Fujiwara, T. Okamoto, Y. Okuda, R. Maekura, T. Kuroki, and I. Yano. Rapid serodiagnosis of Mycobacterium avium-intracellulare complex infection by ELISA with cord factor (trehalose 6, 6'-dimycolate), and serotyping using the glycopeptidolipid antigen. Microbiol. Immunol. 1998. 42: 689-696.

Kasahara, K., I. Sato, K. Ogura, H. Takeuchi, K. Kobayashi, and M. Adachi. Expression of chemokines and induction of rapid cell death in human blood neutrophils by Mycobacterium tuberculosis. J. Infect. Dis. 1998. 178: 127-137.

Kobayashi, K., M. Kai, M. Gidoh, N. Nakata, M. Endoh, R. P. Singh, T. Kasama, and H. Saito. The possible role of interleukin (IL)-12 and interferon-g-inducing factor/IL-18 in protection against experimental Mycobacterium leprae infection in mice. Clin. Immunol. Immunopathol. 1998. 88: 226-231.

Kobayashi, K., N. Nakata, M. Kai, T. Kasama, Y. Hanyuda, and Y. Hatano. Decreased expression of cytokines that induce type 1 helper T cell/interferon-g responses in genetically susceptible mice infected with Mycobacterium avium. Clin. Immunol. Immunopathol. 1997. 85: 112-116.


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