(2009)

1 Masami Yamada, Shiori Toba, Takako Takitoh, Yuko Yoshida, Daisuke Mori, Takeshi Nakamura,Atsuko H Iwane, Toshio Yanagida, Hiroshi Imai, Li-yuan Yu-Lee, et al.
mNUDC is required for plus-end-directed transport of cytoplasmic dynein and dynactins by kinesin-1
The EMBO J 29517-531 (17 December 2009) doi:10.1038/emboj.2009.378 Article

2Yamada M, Yoshida Y, Mori D, Takitoh T, Kengaku M, Umeshima H, Takao K, Miyakawa T, Sato M, Sorimachi H, Wynshaw-Boris A, Hirotsune S.
　 Inhibition of calpain increases LIS1 expression and partially rescues in vivo phenotypes in a mouse model of lissencephaly. Nat Med2009 Oct;15(10):1202-7.

3 Mori D, Yamada M, Mimori-Kiyosue Y, Shirai Y, Suzuki A, Ohno S, Saya H, Wynshaw-Boris A, Hirotsune S.
　An essential role of the aPKC-Aurora A-NDEL1 pathway in neurite elongation by modulation of microtubule dynamics. Nat Cell Biol2009 Sep;11(9):1057-68.

4  Arimura N, Hattori A, Kimura T, Nakamuta S, Funahashi Y, Hirotsune S, Furuta K, Urano T, Toyoshima YY, Kaibuchi K.
　CRMP-2 directly binds to cytoplasmic dynein and interferes with its activity.
　J Neurochem2009Oct;111(2):380-90.

(2008)

5  Yingling J, Youn YH, Darling D, Toyo-Oka K, Pramparo T, Hirotsune S, Wynshaw-Boris A.
　Neuroepithelial stem cell proliferation requires LIS1 for precise spindle orientation and symmetric division.
　Cell2008 Feb 8;132(3):474-86.

6.   Yamada M, Toba S, Yoshida Y, Haratani K, Mori D, Yano Y, Mimori-Kiyosue Y, Nakamura T, Itoh K, Fushiki S, Setou M, Wynshaw-Boris A, Torisawa T, Toyoshima YY, Hirotsune S.
　LIS1 and NDEL1 coordinate the plus-end-directed transport of cytoplasmic dynein.
　EMBO J2008 Oct 8;27(19):2471-83.

7  Toyo-oka K, Mori D, Yano Y, Shiota M, Iwao H, Goto H, Inagaki M, Hiraiwa N, Muramatsu M, Wynshaw-Boris A, Yoshiki A, Hirotsune S.
　 Protein phosphatase 4 catalytic subunit regulates Cdk1 activity and microtubule organization via NDEL1 dephosphorylation. J Cell Biol2008 Mar 24;180(6):1133-47.

(2007)

8. Taya S, Shinoda T, Tsuboi D, Asaki J, Nagai K, Hikita T, Kuroda S, Kuroda K, Shimizu M, Hirotsune S, Iwamatsu A, Kaibuchi K.
　 DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1.
J Neurosci2007 Jan 3;27(1):15-26.

9. Mori D, Yano Y, Toyo-oka K, Yoshida N, Yamada M, Muramatsu M, Zhang D, Saya H, Toyoshima YY, Kinoshita K, Wynshaw-Boris A, Hirotsune S.
　NDEL1 phosphorylation by Aurora-A kinase is essential for centrosomal maturation, separation, and TACC3 recruitment. Mol Cell Biol2007 Jan;27(1):352-67.

(2006)

10.Toyo-oka K, Bowen TJ, Hirotsune S, Li Z, Jain S, Ota S, Escoubet-Lozach L, Garcia-Bassets I, Lozach J, Rosenfeld MG, Glass CK, Eisenman R, Ren B, Hurlin P, Wynshaw-Boris A.
　 Mnt-deficient mammary glands exhibit impaired involution and tumors with characteristics of myc overexpression. Cancer Res2006 Jun 1;66(11):5565-73.

(2005)

11 Toyo-Oka K, Sasaki S, Yano Y, Mori D, Kobayashi T, Toyoshima YY, Tokuoka SM, Ishii S, Shimizu T, Muramatsu M, Hiraiwa N, Yoshiki A, Wynshaw-Boris A, Hirotsune S.
　 Recruitment of katanin p60 by phosphorylated NDEL1, an LIS1 interacting protein, is essential for mitotic cell division and neuronal migration. Hum Mol Genet2005 Nov 1;14(21):3113-28.

12.Sasaki S, Mori D, Toyo-oka K, Chen A, Garrett-Beal L, Muramatsu M, Miyagawa S, Hiraiwa N, Yoshiki A, Wynshaw-Boris A, Hirotsune S.
　 Complete loss of Ndel1 results in neuronal migration defects and early embryonic lethality.
　 Mol Cell Biol2005 Sep;25(17):7812-27.

(2004)

13.Yano Y, Saito R, Yoshida N, Yoshiki A, Wynshaw-Boris A, Tomita M, Hirotsune S.
　A new role for expressed pseudogenes as ncRNA: regulation of mRNA stability of its homologous coding gene.
　J Mol Med2004 Jul;82(7):414-22.

14. Toyo-oka K, Hirotsune S, Gambello MJ, Zhou ZQ, Olson L, Rosenfeld MG, Eisenman R, Hurlin P, Wynshaw-Boris A.
　 Loss of the Max-interacting protein Mnt in mice results in decreased viability, defective embryonic growth and craniofacial defects: relevance to Miller-Dieker syndrome.
　Hum Mol Genet2004 May 15;13(10):1057-67.

15  Hurlin PJ, Zhou ZQ, Toyo-Oka K, Ota S, Walker WL, Hirotsune S, Wynshaw-Boris A. Evidence of mnt-myc antagonism revealed by mnt gene deletion. Cell Cycle2004 Feb;3(2):97-9.

(2003)

16          Toyo-oka K, Shionoya A, Gambello MJ, Cardoso C, Leventer R, Ward HL, Ayala R, Tsai LH, Dobyns W, Ledbetter D, Hirotsune S, Wynshaw-Boris A. 14-3-3epsilon is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller-Dieker syndrome. Nat Genet2003 Jul;34(3):274-85.

17         Tokuoka SM, Ishii S, Kawamura N, Satoh M, Shimada A, Sasaki S, Hirotsune S, Wynshaw-Boris A, Shimizu T. Involvement of platelet-activating factor and LIS1 in neuronal migration.
Eur J Neurosci2003 Aug;18(3):563-70.

18.          Hurlin PJ, Zhou ZQ, Toyo-oka K, Ota S, Walker WL, Hirotsune S, Wynshaw-Boris A. Deletion of Mnt leads to disrupted cell cycle control and tumorigenesis.
EMBO J2003 Sep 15;22(18):4584-96.

19         Hirotsune S, Yoshida N, Chen A, Garrett L, Sugiyama F, Takahashi S, Yagami K, Wynshaw-Boris A, Yoshiki A. An expressed pseudogene regulates the messenger-RNA stability of its homologous coding gene. Nature2003 May 1;423(6935):91-6.

20          Cardoso C, Leventer RJ, Ward HL, Toyo-Oka K, Chung J, Gross A, Martin CL, Allanson J, Pilz DT, Olney AH, Mutchinick OM, Hirotsune S, Wynshaw-Boris A, Dobyns WB, Ledbetter DH. Refinement of a 400-kb critical region allows genotypic differentiation between isolated lissencephaly, Miller-Dieker syndrome, and other phenotypes secondary to deletions of 17p13.3.
Am J Hum Genet2003 Apr;72(4):918-30.

(-2002)

21          Takasuga A, Hirotsune S, Itoh R, Jitohzono A, Suzuki H, Aso H, Sugimoto Y. Establishment of a high throughput EST sequencing system using poly(A) tail-removed cDNA libraries and determination of 36,000 bovine ESTs.
Nucleic Acids Res2001 Nov 15;29(22):E108.

22          Sasaki S, Shionoya A, Ishida M, Gambello MJ, Yingling J, Wynshaw-Boris A, Hirotsune S. A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system.
Neuron2000 Dec;28(3):681-96.

23         Hirano T, Kobayashi N, Itoh T, Takasuga A, Nakamaru T, Hirotsune S, Sugimoto Y. Null mutation of PCLN-1/Claudin-16 results in bovine chronic interstitial nephritis. Genome Res2000 May;10(5):659-63.

24          Fleck MW, Hirotsune S, Gambello MJ, Phillips-Tansey E, Suares G, Mervis RF, Wynshaw-Boris A, McBain CJ. Hippocampal abnormalities and enhanced excitability in a murine model of human lissencephaly.
J Neurosci2000 Apr 1;20(7):2439-50.

25         Kimber WL, Hsieh P, Hirotsune S, Yuva-Paylor L, Sutherland HF, Chen A, Ruiz-Lozano P, Hoogstraten-Miller SL, Chien KR, Paylor R, Scambler PJ, Wynshaw-Boris A. Deletion of 150 kb in the minimal DiGeorge/velocardiofacial syndrome critical region in mouse. Hum Mol Genet1999 Nov;8(12):2229-37.

26          Hirotsune S, Fleck MW, Gambello MJ, Bix GJ, Chen A, Clark GD, Ledbetter DH, McBain CJ, Wynshaw-Boris A. Graded reduction of Pafah1b1 (Lis1) activity results in neuronal migration defects and early embryonic lethality. Nat Genet1998 Aug;19(4):333-9.

27          Hirotsune S, Pack SD, Chong SS, Robbins CM, Pavan WJ, Ledbetter DH, Wynshaw-Boris A. Genomic organization of the murine Miller-Dieker/lissencephaly region: conservation of linkage with the human region. Genome Res1997 Jun;7(6):625-34.

28          Plass C, Shibata H, Kalcheva I, Mullins L, Kotelevtseva N, Mullins J, Kato R, Sasaki H, Hirotsune S, Okazaki Y, Held WA, Hayashizaki Y, Chapman VM. Identification of Grf1 on mouse chromosome 9 as an imprinted gene by RLGS-M. Nat Genet1996 Sep;14(1):106-9.

29         Pecker I, Avraham KB, Gilbert DJ, Savitsky K, Rotman G, Harnik R, Fukao T, Schrock E, Hirotsune S, Tagle DA, Collins FS, Wynshaw-Boris A, Ried T, Copeland NG, Jenkins NA, Shiloh Y, Ziv Y. Identification and chromosomal localization of Atm, the mouse homolog of the ataxia-telangiectasia gene.
Genomics1996 Jul 1;35(1):39-45.

30         Hirotsune S, Takahara T, Sasaki N, Imoto H, Okazaki Y, Eki T, Murakami Y, Abe M, Furuya K, Muramatsu M, Eto Y, Chapman VM, Hayashizaki Y. Construction of high-resolution physical maps from yeast artificial chromosomes using restriction landmark genomic scanning (RLGS).
Genomics1996 Oct 1;37(1):87-95.

31         Barlow C, Hirotsune S, Paylor R, Liyanage M, Eckhaus M, Collins F, Shiloh Y, Crawley JN, Ried T, Tagle D, Wynshaw-Boris A. Atm-deficient mice: a paradigm of ataxia telangiectasia. Cell1996 Jul 12;86(1):159-71.

32.          Okazaki Y, Hirose K, Hirotsune S, Okuizumi H, Sasaki N, Ohsumi T, Yoshiki A, Kusakabe M, Muramatsu M, Kawai J, et al. Direct detection and isolation of restriction landmark genomic scanning (RLGS) spot DNA markers tightly linked to a specific trait by using the RLGS spot-bombing method.
Proc Natl Acad Sci U S A1995 Jun 6;92(12):5610-4.

33.          Hirotsune S, Takahara T, Sasaki N, Hirose K, Yoshiki A, Ohashi T, Kusakabe M, Murakami Y, Muramatsu M, Watanabe S, et al. The reeler gene encodes a protein with an EGF-like motif expressed by pioneer neurons. Nat Genet1995 May;10(1):77-83.

34          Kawai J, Hirose K, Fushiki S, Hirotsune S, Ozawa N, Hara A, Hayashizaki Y, Watanabe S. Comparison of DNA methylation patterns among mouse cell lines by restriction landmark genomic scanning.
Mol Cell Biol1994 Nov;14(11):7421-7.

35          Hirotsune S, Hirose K, Kataoka H, Kuromitsu J, Furuichi Y, Muramatsu M, Matsuda Y, Hayashizaki Y. Spot mapping on the standard profile of restriction landmark genomic scanning (RLGS) of sorted chromosome 20 using methylation-insensitive enzyme. Genomics1994 Dec;24(3):593-6.

36          Hayashizaki Y, Shibata H, Hirotsune S, Sugino H, Okazaki Y, Sasaki N, Hirose K, Imoto H, Okuizumi H, Muramatsu M, et al. Identification of an imprinted U2af binding protein related sequence on mouse chromosome 11 using the RLGS method. Nat Genet1994 Jan;6(1):33-40.

37          Hayashizaki Y, Hirotsune S, Okazaki Y, Shibata H, Akasako A, Muramatsu M, Kawai J, Hirasawa T, Watanabe S, Shiroishi T, et al. A genetic linkage map of the mouse using restriction landmark genomic scanning (RLGS). Genetics1994 Dec;138(4):1207-38.

38          Kawai J, Hirotsune S, Hirose K, Fushiki S, Watanabe S, Hayashizaki Y. Methylation profiles of genomic DNA of mouse developmental brain detected by restriction landmark genomic scanning (RLGS) method. Nucleic Acids Res1993 Dec 11;21(24):5604-8.

39        Hirotsune S, Shibata H, Okazaki Y, Sugino H, Imoto H, Sasaki N, Hirose K, Okuizumi H, Muramatsu M, Plass C, et al. Molecular cloning of polymorphic markers on RLGS gel using the spot target cloning method. Biochem Biophys Res Commun1993 Aug 16;194(3):1406-12.

40          Hirotsune S, Hatada I, Komatsubara H, Nagai H, Kuma K, Kobayakawa K, Kawara T, Nakagawara A, Fujii K, Mukai T, et al. New approach for detection of amplification in cancer DNA using restriction landmark genomic scanning. Cancer Res1992 Jul 1;52(13):3642-7.

41          Hayashizaki Y, Hirotsune S, Hatada I, Tamatsukuri S, Miyamoto C, Furuichi Y, Mukai T. A new method for constructing NotI linking and boundary libraries using a restriction trapper. Genomics1992 Nov;14(3):733-9.

42.          Hatada I, Hayashizaki Y, Hirotsune S, Komatsubara H, Mukai T. A genomic scanning method for higher organisms using restriction sites as landmarks. Proc Natl Acad Sci U S A1991 Nov 1;88(21):9523-7.

43.          Funae Y, Wada S, Imaoka S, Hirotsune S, Tominaga M, Tanaka S, Kishimoto T, Maekawa M. Chromatographic separation of alpha 1-acid glycoprotein from alpha 1-antitrypsin by high-performance liquid chromatography using a hydroxyapatite column. J Chromatogr1986 Aug 22;381(1):149-52.