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業績紹介

平成28年（2016年）の業績一覧

著書：欧文

著書、学術論文等の名称 発表 発行所、発表雑誌等の名称 著者名
THERAPEUTIC TARGETS FOR INFLAMMATION AND CANCER-Novel Therapies for Digestive Diseases.
The degradation system of prostaglandin E2 in gastrointestinal cancer		 2017 Wolrd Scientific Tanigawa T, Watanabe T, Takeda S, Tatsuwaki H, Shiba M, Tominaga K, Fujiwara Y,Arakawa T

著書：和文

著書、学術論文等の名称 発表 発行所、発表雑誌等の名称 著者名
1.機能性消化管疾患ガイドライン2014－過敏性腸症候群 今日の治療指針2017
1839-1842		 藤原靖弘、荒川哲男
Ⅰ．③病態生理　A.　食道、胃食道接合部の運動生理 2017 食道・胃・十二指腸疾患のアップデート34-37 沢田明也、藤原靖弘
Ⅲ.　病態生理 ① 上部消化管　A.　食道、胃食道接合部の運動生理 ガイドライン準拠　消化器病診療マニュアル 沢田明也、藤原靖弘
逆流性食道炎 診断と治療　消化器
診断基準と分類法		 沢田明也、須川貴史、藤原靖弘

原著論文：和文

著書、学術論文等の名称 発表 発行所、発表雑誌等の名称 著者名
1. Propensity scoreマッチング解析を用いた非ステロイド系抗炎症薬服用関節リウマチ患者における小腸傷害の発症と高年齢との関連性の検討 2016 日本高齢消化器病学会誌
18 (2):87-93		 谷川徹也、渡辺俊雄、斯波将次、灘谷祐二、永見康明、杉森聖司、山上博一、富永和作、藤原靖弘、荒川哲男、小池達也
2. NSAIDs起因性小腸傷害に対するNLRP3インフラマソームを介したコルヒチンの効果 2016 潰瘍
43: 67-70		 大谷恒史、渡辺俊雄、灘谷祐二、谷川徹也、富永和作、藤原靖弘、荒川哲男

原著論文：欧文

著書、学術論文等の名称 発表 発行所、発表雑誌等の名称 著者名
1. Mechanisms of NLRP3 inflammasome activation and its role in NSAID-induced enteropathy. 2016 Mucosal Immunol.
9(3):659-68. 		Higashimori A, Watanabe T, Nadatani Y, Takeda S, Otani K, Tanigawa T, Yamagami H, Shiba M, Tominaga K, Fujiwara Y, Arakawa T.
2. Locoregional steroid injection prevents stricture formation after endoscopic submucosal dissection for esophageal cancer: a propensity score matching analysis. 2016 Surg Endosc.
30(4):1441-9.		 Nagami Y, Shiba M, Tominaga K, Minamino H, Ominami M, Fukunaga S, Sugimori S, Tanigawa T, Yamagami H, Watanabe K, Watanabe T, Fujiwara Y, Arakawa T.
3. Reduction of prostaglandin transporter predicts poor prognosis associated with angiogenesis in gastric adenocarcinoma.
（学位指導論文）		 2016 J Gastroenterol Hepatol.
31(2):376-83
 Takeda S, *Tanigawa T, Watanabe T, Tatsuwaki H, Nadatani Y, Otani K, Nagami Y, Tanaka F, Kamata N, Yamagami H, Shiba M, Tominaga K, Fujiwara Y, Muguruma K, Ohira M, Hirakawa K, Arakawa T.
4. Comparison of Risk Factors Between Small Intestinal Ulcerative and Vascular Lesions in Occult Versus Overt Obscure Gastrointestinal Bleeding. 2016 Dig Dis Sci.
61(2):533-41. 		Okamoto J, Tominaga K, Sugimori S, Kato K, Minamino H, Ominami M, Fukunaga S, Nagami Y, Kamata N, Yamagami H, Tanigawa T, Shiba M, Watanabe T, Fujiwara Y, Arakawa T.
5. Structural changes in gastric glial cells and delayed gastric emptying as responses to early life stress and acute adulthood stress in rats. 2016 Life Sci.
148:254-9.		 Tominaga K, Fujikawa Y, Tanaka F, Kamata N, Yamagami H, Tanigawa T, Watanabe T, Fujiwara Y, Arakawa T.
6. Long-Term Benefits of Smoking Cessation on Gastroesophageal Reflux Disease and Health-Related Quality of Life. 2016 PLoS One.
11(2):e0147860		 Kohata Y, Fujiwara Y, Watanabe T, Kobayashi M, Takemoto Y, Kamata N, Yamagami H, Tanigawa T, Shiba M, Watanabe T, Tominaga K, Shuto T, Arakawa T.
7. Disorder of autonomic nervous system and its vulnerability to external stimulation in functional dyspepsia. 2016 J Clin Biochem Nutr.
58(2):161-5.		 Tominaga K, Fujikawa Y, Tsumoto C, Kadouchi K, Tanaka F, Kamata N, Yamagami H, Tanigawa T, Watanabe T, Fujiwara Y, Arakawa T.
8. Characteristics of Sleep Disturbances in Patients with Gastroesophageal Reflux Disease. 2016 Intern Med. 55(12):1511-7. Iwakura N, Fujiwara Y, Shiba M, Ochi M, Fukuda T, Tanigawa T, Yamagami H, Tominaga K, Watanabe T, Arakawa T.
9. Long-term prognosis of expanded-indication differentiated early gastric cancer treated with endoscopic submucosal dissection or surgery using propensity score analysis. 2016 Gastrointest Endosc.
2016 Jun 27. [Epub ahead of print]		 Fukunaga S, Nagami Y, Shiba M, Ominami M, Tanigawa T, Yamagami H, Tanaka H, Muguruma K, Watanabe T, Tominaga K, Fujiwara Y, Ohira M, Hirakawa K, Arakawa T.
10. Alteration of Esophageal Microbiome by Antibiotic Treatment Does Not Affect Incidence of Rat Esophageal Adenocarcinoma. 2016 Dig Dis Sci. 2016 Jul 26. [Epub ahead of print] Sawada A, Fujiwara Y, Nagami Y, Tanaka F, Yamagami H, Tanigawa T, Shiba M, Tominaga K, Watanabe T, Gi M, Wanibuchi H, Arakawa T.
11. Prediction of Poor Response to Modified Neuroleptanalgesia with Midazolam for Endoscopic Submucosal Dissection for Esophageal Squamous Cell Carcinoma. 2016 Digestion. 2016 Aug 20;94(2):73-81. Ominami M, Nagami Y, Shiba M, Tominaga K, Maruyama H, Okamoto J, Kato K, Minamino H, Fukunaga S, Sugimori S, Yamagami H, Tanigawa T, Watanabe T, Fujiwara Y, Arakawa T.
12. Colchicine prevents NSAID-induced small intestinal injury by inhibiting activation of the NLRP3 inflammasome. 2016 Sci Rep. 2016 Sep 2;6:32587. doi: 10.1038/srep32587. Otani K, Watanabe T, Shimada S, Takeda S, Itani S, Higashimori A, Nadatani Y, Nagami Y, Tanaka F, Kamata N, Yamagami H, Tanigawa T, Shiba M, Tominaga K, Fujiwara Y, Arakawa T.
13. Similar Efficacy of Proton-Pump Inhibitors vs H2-Receptor Antagonists in Reducing Risk of Upper Gastrointestinal Bleeding or Ulcers in High-risk Users of Low-dose Aspirin. 2016 Gastroenterology. 2016 Sep 15. pii: S0016-5085(16)35031-4. doi: 10.1053/j.gastro.2016.09.006. [Epub ahead of print] Chan FK, Kyaw M, Tanigawa T, Higuchi K, Fujimoto K, Cheong PK, Lee V, Kinoshita Y, Naito Y, Watanabe T, Ching JY, Lam K, Lo A, Chan H, Lui R, Tang RS, Sakata Y, Tse YK, Takeuchi T, Handa O, Nebiki H, Wu JC, Abe T, Mishiro T, Ng SC, Arakawa T.
14. Hybrid therapy with locoregional steroid injection and polyglycolic acid sheets to prevent stricture after esophageal endoscopic submucosal dissection. 2016 Endosc Int Open. 2016 Sep;4(9):E1017-22. doi: 10.1055/s-0042-111906. Epub 2016 Aug 25. Nagami Y, Shiba M, Tominaga K, Ominami M, Fukunaga S, Sugimori S, Tanaka F, Kamata N, Tanigawa T, Yamagami H, Watanabe T, Fujiwara Y, Arakawa T.
15. Concentration of Glial Cell Line-Derived Neurotrophic Factor Positively Correlates with Symptoms in Functional Dyspepsia. 2016 Dig Dis Sci. 2016 Dec;61(12):3478-3485. Tanaka F, Tominaga K, Fujikawa Y, Nagami Y, Kamata N, Yamagami H, Tanigawa T, Shiba M, Watanabe T, Fujiwara Y, Arakawa T.
16. Sleep disturbances in Japanese patients with inflammatory bowel disease and their impact on disease flare. 2016 Springerplus. 2016 Oct 13;5(1):1792. Uemura R, Fujiwara Y, Iwakura N, Shiba M, Watanabe K, Kamata N, Yamagami H, Tanigawa T, Watanabe T, Tominaga K, Arakawa T.
17. A comparison between capsule endoscopy and double balloon enteroscopy using propensity score-matching analysis in patients with previous obscure gastrointestinal bleeding. 2016 Scand J Gastroenterol. 2016 Nov 13:1-6. [Epub ahead of print] Kakiya Y, Shiba M, Okamoto J, Kato K, Minamino H, Ominami M, Fukunaga S, Nagami Y, Sugimori S, Tanigawa T, Yamagami H, Watanabe T, Tominaga K, Fujiwara Y, Arakawa T.
18. NLRP3 inflammasome has a protective effect against oxazolone-induced colitis: a possible role in ulcerative colitis. 2016 Sci Rep. 2016 Dec 14;6:39075. Itani S, Watanabe T, Nadatani Y, Sugimura N, Shimada S, Takeda S, Otani K, Hosomi S, Nagami Y, Tanaka F, Kamata N, Yamagami H, Tanigawa T, Shiba M, Tominaga K, Fujiwara Y, Arakawa T.
19. The five-year survival rate after endoscopic submucosal dissection for superficial esophageal squamous cell neoplasia. 2016 Dig Liver Dis. 2016 Dec 21. pii: S1590-8658(16)30829-5. doi:10.1016/j.dld.2016.12.009. [Epub ahead of print] Nagami Y, Ominami M, Shiba M, Minamino H, Fukunaga S, Kameda N, Sugimori S, Machida H, Tanigawa T, Yamagami H, Watanabe T, Tominaga K, Fujiwara Y, Arakawa T.
20. Neutrophil-to-Lymphocyte Ratio for Predicting Loss of Response to Infliximab in Ulcerative Colitis. 2017 PLoS One. 2017 Jan 11;12(1):e0169845. doi: 10.1371/journal.pone.0169845. Nishida Y, Hosomi S, Yamagami H, Yukawa T, Otani K, Nagami Y, Tanaka F, Taira K, Kamata N, Tanigawa T, Shiba M, Watanabe K, Watanabe T, Tominaga K, Fujiwara Y.
21. Randomized phase III study of bevacizumab plus FOLFIRI and bevacizumab plus mFOLFOX6 as first-line treatment for patients with metastatic colorectal cancer (WJOG4407G). 2017 Ann Oncol. 2016 Aug;27(8):1539-46. Yamazaki K, Nagase M, Tamagawa H, Ueda S, Tamura T, Murata K, Eguchi Nakajima T, Baba E, Tsuda M, Moriwaki T, Esaki T, Tsuji Y, Muro K, Taira K, Denda T, Funai S, Shinozaki K, Yamashita H, Sugimoto N, Okuno T, Nishina T, Umeki M, Kurimoto T, Takayama T, Tsuji A, Yoshida M, Hosokawa A, Shibata Y, Suyama K, Okabe M, Suzuki K, Seki N, Kawakami K, Sato M, Fujikawa K, Hirashima T, Shimura T, Taku K, Otsuji T, Tamura F, Shinozaki E, Nakashima K, Hara H, Tsushima T, Ando M, Morita S, Boku N, Hyodo I.
22. Analysis of the Risk Factors of Surgery after Endoscopic Balloon Dilation for Small Intestinal Strictures in Crohn’s Disease Using Double-balloon Endoscopy 2017 Intern Med.
in press		 Nishida Y, Hosomi S, Yamagami H, Yukawa T, Otani K, Nagami Y, Tanaka F, Kamata N, Tanigawa T, Shiba M, Watanabe T, Tominaga K, Fujiwara Y, Arakawa T.
23. Single locoregional triamcinolone injection immediately after esophageal endoscopic submucosal dissection prevents stricture formation 2017 Clinical and Translational Gastroenterology. 2017 in press Nagami Y, Shiba M, Ominami M, Sakai T, Minamino H, Fukunaga S, Sugimori S, Tanaka F, Kamata N, Tanigawa T, Yamagami H, Watanabe T, Tominaga K, Fujiwara Y, Arakawa T.
24. A comparison of short-term therapeutic efficacy between infliximab and tacrolimus for moderate to severe ulcerative colitis. 2017 Rom J Intern Med. 2017 Feb 1. pii: /j/rjim.ahead-of-print/rjim-2017-0012/rjim-2017-0012.xml. doi: 10.1515/rjim-2017-0012. [Epub ahead of print] Yamagami H, Nishida Y, Nagami Y, Hosomi S, Yukawa T, Otani K, Tanaka F, Taira K, Kamata N, Tanigawa T, Shiba M, Watanabe T, Fujiwara Y.
25. Brushing the distal biliary stricture of surrounding the papilla increased the risk of post-endoscopic retrograde cholangiopancreatography pancreatitis: A retrospective study using propensity score analysis 2017 United European Gastroenterology Journal (in press) Kato K, Sugimori S, Kakiya Y, et al.
26. Liquid-containing Refluxes and Acid Refluxes May Be Less Frequent in the Japanese Population Than in Other Populations: Normal Values of 24- hour Esophageal Impedance and pH Monitoring. 2016 J Neurogastroenterol Motil. 2016;22(4):620-629. Kawamura O, Kohata Y, Kawami N, Iida H, Kawada A, Hosaka H, Shimoyama Y, Kuribayashi S, Fujiwara Y, Iwakiri K, Inamori M, Kusano M, Hongo M.
27. Associations among gastroesophageal reflux disease, psychological stress, and sleep disturbances in Japanese adults. 2017 Scand J Gastroenterol. 2017 Jan;52(1):44-49 Okuyama M, Takaishi O, Nakahara K, Iwakura N, Hasegawa T, Oyama M, Inoue A, Ishizu H, Satoh H, Fujiwara Y.

総説：和文

著書、学術論文等の名称 発表 発行所、発表雑誌等の名称 著者名
1. 好酸球性食道炎の分子機構にもとづく治療戦略 2016 G. I. Research
24 (3): 181-186
 藤原靖弘、須川貴史、橋本篤、谷川徹也、富永和作
2. 性消化管疾患　診療ガイドラインにおける心身医学の新たな役割 FD　診療ガイドライン2014 2016 心身医学 (0385-0307)56巻10号 Page977-985 富永和作、藤川佳子、田中史生、谷川徹也、渡辺俊雄、藤原靖弘、荒川哲男
3. 【脳腸相関　各種メディエーター、腸内フローラから食品の機能性まで】 過敏性腸症候群(IBS)における腸管グリア細胞の変化 2016 臨床栄養 128(6):737-740 藤川佳子、富永和作、田中史生、谷川徹也、渡辺俊雄、藤原靖弘、荒川哲男
4. 【逆流性食道炎-最新の治療動向-】 日本人における逆流性食道炎の疫学および臨床像 2016 日本臨床 74(8):1257-1261 藤原靖弘
5. 【難治性逆流性食道炎/NERDを診る】 難治性逆流性食道炎/NERDの鑑別疾患・合併疾患は何か?どう対応するか? 2016 消化器の臨床 19(2):107-111 須川貴史、藤原靖弘、荒川哲男
6. 内科診断の道しるべ　60．腹部膨満感・もたれ 2016 medicina 53(4) :310-314 須川貴史、藤原靖弘、荒川哲男
7. クローン病における生物学的製剤治療の現状と問題点；効果減弱例に対する血球除去療法の位置づけと今後の展望 2016 日本アフェレシス学会雑誌　35(2)：138-141 鎌田紀子
8. 診断と治療のABC　睡眠時無呼吸症候群　胃食道逆流症 2016 最新医学社　別冊 119: 289-296 上村理沙、須川貴史、藤原靖弘

総説：欧文

著書、学術論文等の名称 発表 発行所、発表雑誌等の名称 著者名
1. Double-balloon endoscopy WAS effective in diagnosing small intestinal duplication: a case report. 2016 Springerplus. 2016 Sep 19;5(1):1598. doi: 10.1186/s40064-016-3256-4. eCollection 2016. Nadatani Y, Watanabe T, Sugawa T, Eguchi S, Shimada S, Otani K, Yamagami H, Tanigawa T, Shiba M, Tominaga K, Fujiwara Y, Arakawa T.
2. A novel endoscopic technique for closure of a large esophageal perforation by using the clip and snare method with the pre-looping technique 2016 Endoscopy. 2016;48 Suppl 1:E250-1. Nagami Y, Shiba M, Ominami M, Tominaga K, Watanabe T, Fujiwara Y, Arakawa T.
3. Use of PGA Sheets in the Endoscopic Closure of a Perforation After Endoscopic Submucosal Dissection for Gastric-Tube Cancer. 2016 Am J Gastroenterol. 2016 Jun;111(6):768. Nagami Y, Shiba M, Arakawa T.
4. Endoscopic submucosal dissection as diagnostic treatment for gastric granular cell tumor confined to the submucosa 2016 General Medicine. 2016 4:2
http://dx.doi.org/10.4172/2327-5146.1000229		 Yamamura M, Nagami Y, Tominaga K,
Shiba M, Watanabe T, Fujiwara Y, Arakawa T.
5. A Case of Non-Swelling Autoimmune Pancreatitis with Multiple Pancreatic
6. Pseudocysts		 2016 JOP.J Pancreas. 2016. Sep 08;17(5): 543-548 Maruyama H,Tominaga K, Kato K, Nagami Y, Sugimori S, Shiba M, Watanabe T, Fujiwara Y, Kubo Y, Ohsawa M

症例報告：和文

著書、学術論文等の名称 発表 発行所、発表雑誌等の名称 著者名
1. 遷延する低血糖をきたしたinsulin-likegrowth factor-II産生肝細胞癌の1例 2017 日本消化器病学会雑誌
114 (2): 256-263		 中田理恵子ほか

その他：和文

著書、学術論文等の名称 発表 発行所、発表雑誌等の名称 著者名
1. 胃食道逆流症：診断と治療の最前線 2016 阿倍野区医師会報 No.345: 2-5 谷川徹也