近年の業績(2005年以降)

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2007年

Kitano A, Saika S, Yamanaka O, Ikeda K, Okada Y, Shirai K, Reinach PS.
Emodin suppression of ocular surface inflammatory reaction.
Invest Ophthalmol Vis Sci. 2007 Nov;48(11):5013-22.

Yamanaka O, Saika S, Ohnishi Y, Kim-Mitsuyama S, Kamaraju AK, Ikeda K.
Inhibition of p38MAP kinase suppresses fibrogenic reaction in conjunctiva in mice.
Mol Vis. 2007 Sep 18;13:1730-9.

Okada Y, Ikeda K, Yamanaka O, Miyamoto T, Kitano A, Kao WW, Saika S.
TNFalpha suppression of corneal epithelium migration.
Mol Vis. 2007 Aug 14;13:1428-35.

Saika S, Yamanaka O, Okada Y, Miyamoto T, Kitano A, Flanders KC, Ohnishi Y, Nakajima Y, Kao WW, Ikeda K.
Effect of overexpression of PPARgamma on the healing process of corneal alkali burn in mice.
Am J Physiol Cell Physiol. 2007 Jul;293(1):C75-86.

Fujita S, Saika S, Kao WW, Fujita K, Miyamoto T, Ikeda K, Nakajima Y, Ohnishi Y.
Endogenous TNFalpha suppression of neovascularization in corneal stroma in mice.
Invest Ophthalmol Vis Sci. 2007 Jul;48(7):3051-5.

Saika S, Yamanaka O, Nishikawa-Ishida I, Kitano A, Flanders KC, Okada Y, Ohnishi Y, Nakajima Y, Ikeda K.
Effect of Smad7 gene overexpression on transforming growth factor beta-induced retinal pigment fibrosis in a proliferative vitreoretinopathy mouse model.
Arch Ophthalmol. 2007 May;125(5):647-54. PubMed PMID: 17502504.

Otogawa K, Kinoshita K, Fujii H, Sakabe M, Shiga R, Nakatani K, Ikeda K, Nakajima Y, Ikura Y, Ueda M, Arakawa T, Hato F, Kawada N.
Erythrophagocytosis by liver macrophages (Kupffer cells) promotes oxidative stress, inflammation, and fibrosis in a rabbit model of steatohepatitis: implications for the pathogenesis of human nonalcoholic steatohepatitis.
Am J Pathol. 2007 Mar;170(3):967-80.

Sakata H, Sakabe M, Matsui H, Kawada N, Nakatani K, Ikeda K, Yamagishi T, Nakajima Y.
Rho kinase inhibitor Y27632 affects initial heart myofibrillogenesis in cultured chick blastoderm.
Dev Dyn. 2007 Feb;236(2):461-72.

El-Karef A, Kaito M, Tanaka H, Ikeda K, Nishioka T, Fujita N, Inada H, Adachi Y, Kawada N, Nakajima Y, Imanaka-Yoshida K, Yoshida T.
Expression of large tenascin-C splice variants by hepatic stellate cells/myofibroblasts in chronic hepatitis C.
J Hepatol. 2007 Apr;46(4):664-73.

Kinoshita K, Iimuro Y, Otogawa K, Saika S, Inagaki Y, Nakajima Y, Kawada N, Fujimoto J, Friedman SL, Ikeda K.
Adenovirus-mediated expression of BMP-7 suppresses the development of liver fibrosis in rats.
Gut. 2007 May;56(5):706-14.

Nakatani K, Ikeda K, Nakajima Y, Seki S.
Expression of molecules with a potential for modulating interaction with extracellular matrices on hepatic stellate cells: neural cell adhesion molecules and osteonectin.
In: Dillon KH (ed), Trends in Liver Cirrhosis Research, Nova Science Publishers Inc, NY, pp 89-127, 2007

Kojima K, Nagata K, Matsubara T, Yamazoe Y. (2007)
Broad but distinct role of pregnane x receptor on the expression of individual cytochrome p450s in human hepatocytes.
Drug Metab Pharmacokinet 22:276-286

Kamiyama Y, Matsubara T, Yoshinari K, Nagata K, Kamimura H, Yamazoe, Y. (2007)
Role of human hepatocyte nuclear factor 4alpha in the expression of drug-metabolizing enzymes and transporters in human hepatocytes assessed by use of small interfering RNA.
Drug Metab Pharmacokinet 22(4):287-298.

Matsubara T, Noracharttiyapot W, Toriyabe T, Yoshinari K, Nagata K and Yamazoe Y. (2007)
Assessment of human pregnane X receptor-involvement in pesticide-mediated activation of CYP3A4 gene.
Drug Metab Dispos 35(5):728-733